Irène Friedli grew up in Räuchlisberg, Switzerland, and completed her studies at the Basel Academy of Music with a soloist diploma. The contralto furthered her studies in Dietrich Fischer-Dieskau's interpretation class in Berlin, attended masterclasses with Brigitte Fassbaender and continued her training with Helen Keller. She won numerous prizes at international song competitions. She has been an ensemble member at Zurich Opera House since 1994. Here, she has performed roles including the Second and Third Lady ("Die Zauberflöte"), Mercédès ("Carmen"), the title role in Ravel's "L’Enfant et les sortilèges", Elsbeth in "Schlafes Bruder", Lily in "Harley", Annina and Flora ("La traviata"), Flosshilde ("Das Rheingold", "Götterdämmerung"), Marcellina ("Le nozze di Figaro"), Emilia ("Otello"), Lucia ("Cavalleria rusticana"), Olga in Peter Eötvös' "Three Sisters", Marthe in Gounod's "Faust", Margret ("Wozzeck"), Lovis in Jörn Arnecke's "Ronja Räubertochter", a Flower Maiden and the Voice from Above ("Parsifal"), Clotilde ("Norma"), Mother/Other Mother ("Coraline"), the Card Dealer ("Arabella") and the Nurse ("Boris Godunov"). In the world premiere of the family opera "Odyssee", she portrayed Eurycleia/Mother, and in "Girl with a Pearl Earring", Tanneke. In 2012, she made a guest appearance at the Opéra Bastille in Paris. Most recently, she has appeared in Zurich in roles including Filipyevna in "Eugene Onegin", Tisbe in "La Cenerentola", the Head Cook in "Amerika", Annina in "Der Rosenkavalier" and Gertrud/the Witch in "Hänsel und Gretel". In the 2026/27 season, she appears in "Alice in Wonderland", "Roméo et Juliette", "Le nozze di Figaro" and "Elektra".